Download Biochemistry and Genetics Flash Cards by Suzanne Baron PDF

By Suzanne Baron

Clinical circumstances offer whole, concise insurance of the biochemical and genetic illnesses verified at the USMLE Step 1 and in uncomplicated technological know-how courses.

  • A robust specialize in the scientific elements of biochemical and genetic ailment
  • Emphasizes boardrelevant insurance
  • Easily evaluate and distinction illnesses
  • Each disease-specific card incorporates a scientific vignette
  • Important illness proof are highlighted for quick review

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On physical examination, he is tachycardic, appears jaundiced, and has mild splenomegaly. You order serum studies, which show low hemoglobin, low hematocrit, and elevated indirect bilirubin. You begin to suspect that this patient suffers from an X-linked recessive disorder triggered by his current TB prophylaxis, and you decide to consult an infectious disease specialist about alternative regimens that will not cause his current symptoms. Glucose-6-Phosphate Dehydrogenase Deficiency Š A 14-year-old boy presents for a routine physical examination to participate in high school athletics.

Transfers e- to O2, which is combined with hydrogen to form H 2 O. Inhibited by cyanide, CO, and sodium azide. Complex V (ATP synthase): Contains a proton channel that allows for protons to cross into the matrix, using the proton gradient energy to form ATP. Inhibited by oligomycin (blocks H+ channel). 5 ATP. THE CHEMIOSMOTIC HYPOTHESIS Electron transport causes H+ ions to be pumped from the mitochondrial matrix into the intermembrane space, thereby resulting in the formation of an electrical and pH gradient across the inner mitochondrial membrane.

General pathway: There are two phases in sphingolipid synthesis. The first phase involves the formation of the ceramide core, which is produced by the combination of palmitoyl-CoA, serine, and a fatty acyl-CoA molecule. There are several possible pathways in the second phase of sphingolipid synthesis, which result in the formation of the different sphingolipids. In general though, the second phase involves the addition of a specific compound (eg, phosphocholine, glucose, galactose, sulfate, etc) to the hydroxyl group on the terminal carbon of the ceramide molecule.

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